We engineer adaptive living systems that sense, compute, and heal. Our group integrates synthetic biological intelligence, digital twins, and wireless bioelectronics to realise responsive therapeutics and embodied artificial intelligence.
Our lab collaborates across biology, engineering, and clinical sciences to prototype future healthcare systems. We combine intelligent biomaterials, neural interfaces, and in-silico simulations to understand and control cellular computation.
We develop living substrates that compute. Bioprinted neuronal cultures and glial networks are engineered to exhibit memory, logic, and adaptive response. Through closed-loop AI control and multielectrode interrogation, we stabilise and modulate dynamics to explore embodied intelligence in vitro.
We biofabricate multicellular brain-like networks using in-situ bioprinting, dynamic bioinks, and microfluidic assembly. Our EPSRC and InnovateUK platforms integrate 3D scaffolds, MEAs, and AI for patient-specific modelling, enabling next-generation assembloids for cancer, cognition, and repair.
Our group pioneers hybrid links that bridge biology and machines. We design ultrasonic, electromagnetic, and optical channels to power, sense, and modulate living neural constructs. These interfaces underpin our BRAINET and πWPIT efforts, enabling secure, cloud-integrated neuromodulation and real-time bioelectronic control.
Our work pioneers synthetic biological intelligence, in-vitro neural computation, and secure wireless biointerfaces — uniting AI, biofabrication, and embodied biocomputing for next-generation health and cognitive technologies.
We create programmable living systems — from astrocyte-based logic gates to neural computation circuits — to model, sense, and actuate with in vitro biological substrates guided by AI.
We engineer assembloids integrating neurons, glia, and tumours using dynamic bioinks and in-situ printing. These living circuits are benchmarked via electrophysiology and integrated with digital twins for AI-driven design.
Through projects like πWPIT and BRAINET, we design secure ultrasonic and electromagnetic interfaces that enable real-time neural stimulation and closed-loop feedback for personalised implants and in vitro constructs.
Platforms combining wet-lab, computational, and cyber-physical stacks to accelerate discovery.
Data-driven surrogates predict tissue dynamics and personalise therapies, powering projects like the MSCA STOICISM fellowship and the IEEE T-MBMC multiscale pharmacology roadmap.
Customised bioinks and responsive scaffolds, advanced through BBSRC IAA awards and Innovate UK partnerships, enable organoid and tissue-on-chip fabrication.
High-density electrophysiology with Axion platforms captures spatiotemporal signalling for network control, featured in Royal Society Open Science and IEEE TMBMC studies.
FET-Open GLADIATOR and IEEE TMBMC work demonstrate ultrasonic and electromagnetic powering strategies for implanted bioelectronics.
Competitive grants supporting translational biohybrid intelligence and clinical impact.
| Role | Programme | Years |
|---|---|---|
| PI | UKRI BBSRC IAA Engagement Award — Optimisation of exosome-based therapies from 3D bioprinted stem cell structures | 2023–2024 |
| Co-I | UKRI BBSRC Pioneers Award — ROS signalling in plants: uncovering new communication pathways | 2024–2026 |
| PI | Innovate UK Knowledge Transfer Partnership — 3D bioprinting technology with iMakr Group | 2022–2024 |
| PI | MSCA Individual Fellowship — STOICISM: Stochastic communication inside cortical microcolumns | 2019–2022 |
| PI | WIT Presidential PhD Funding — Internet of Nano Things for next-generation theranostics | 2019–2023 |
| Co-I | EU FET-Open GLADIATOR — Autonomous nanonetworks for brain theranostics | 2018–2022 |
| PI | Enterprise Ireland Commercialisation Fund — Clinical Data as a Service (CDaaS) | 2018–2019 |
| PI | Irish Research Council Postdoctoral Fellowship — Molecular communication control for Alzheimer’s therapies | 2016–2018 |
Collaborations span the European Commission, UKRI councils, Enterprise Ireland, and industrial partners.
We welcome doctoral candidates, postdoctoral fellows, and collaborators who want to push the boundaries of living intelligence.
Students: PhD projects in living computation and regenerative biohybrids are open — apply now.
Collaborators: We partner with clinicians, device engineers, and ethicists. Let’s co-design the future of biohybrid therapeutics — contact us.
Open science: Explore datasets, code, and protocols on GitHub.
International press highlights our breakthroughs in nano-networks, biohybrids, and neural therapeutics.
